L-Methioninol
- Name L-Methioninol
- CAS 2899-37-8
- Purity 99%
Product Details
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1.What is the L-Methioninol ?
L-Methioninol is a methionine derivative that increases bladder excitability by inhibiting stretch-dependent K+ channels.
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63-68-3,26062-47-5,58576-49-1
L-methionine
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2899-37-8
(S)-methioninol
| Conditions | Yield |
|---|---|
|
With
lithium borohydride; chloro-trimethyl-silane;
In
tetrahydrofuran;
at 20 ℃;
for 36h;
|
100%
|
|
With
lithium borohydride; chloro-trimethyl-silane;
In
tetrahydrofuran;
for 24h;
Ambient temperature;
|
94%
|
|
With
sodium tetrahydroborate;
|
89%
|
|
With
dimethylsulfide borane complex;
In
tetrahydrofuran;
25 deg C, 1h, then reflux, 16h;
|
85%
|
|
With
dimethylsulfide borane complex;
In
tetrahydrofuran;
for 16h;
Heating;
|
85%
|
|
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
for 4h;
Heating;
|
79%
|
|
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
for 16h;
Heating;
|
78%
|
|
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
Heating;
|
76%
|
|
With
sodium hydroxide; chloro-trimethyl-silane; lithium borohydride;
In
methanol;
|
75%
|
|
With
sodium hydroxide; chloro-trimethyl-silane;
In
methanol;
|
75%
|
|
With
sodium tetrahydroborate; iodine;
In
tetrahydrofuran;
for 18h;
Heating;
|
65%
|
|
With
sodium tetrahydroborate; iodine;
In
tetrahydrofuran;
Inert atmosphere;
Reflux;
|
65%
|
|
With
sodium tetrahydroborate; iodine;
In
tetrahydrofuran;
Heating;
|
62.02%
|
|
reduction;
|
|
|
With
sodium hydroxide; sodium tetrahydroborate; sulfuric acid;
Yield given. Multistep reaction;
1.) THF, ether, room temp., overnight 2.) reflux, 3 h;
|
|
|
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
heating;
|
|
|
With
sodium tetrahydroborate; amberlyst-15; lithium chloride;
Yield given. Multistep reaction;
1.) CH3OH; 2.) THF, reflux, 3-4 h;
|
|
|
With
lithium borohydride; chloro-trimethyl-silane;
In
tetrahydrofuran;
at 0 ℃;
for 12h;
|
|
|
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
for 6h;
Heating;
|
|
|
|
|
|
Multi-step reaction
with
2
steps
1.1: thionyl chloride / Reflux
2.1: sodium tetrahydroborate / tetrahydrofuran / 0.25 h / 65 °C
2.2: 65 °C
With
sodium tetrahydroborate; thionyl chloride;
In
tetrahydrofuran;
|
|
|
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
Reflux;
Inert atmosphere;
|
|
|
With
sodium tetrahydroborate; iodine;
|
|
|
L-methionine;
With
sodium tetrahydroborate; iodine;
In
tetrahydrofuran;
for 25.5h;
Reflux;
Inert atmosphere;
With
potassium hydroxide;
In
water;
for 6h;
Reflux;
Inert atmosphere;
|
|
|
L-methionine;
With
sodium tetrahydroborate; sulfuric acid;
In
tetrahydrofuran; diethyl ether;
at 0 - 20 ℃;
Inert atmosphere;
With
hydrogenchloride;
In
tetrahydrofuran; diethyl ether; water;
at 20 ℃;
for 2h;
Inert atmosphere;
With
sodium hydroxide;
In
tetrahydrofuran; diethyl ether; water;
at 20 ℃;
for 3h;
Inert atmosphere;
|
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10332-17-9,874219-77-9
Met-OMe
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2899-37-8
(S)-methioninol
| Conditions | Yield |
|---|---|
|
Met-OMe;
With
sodium tetrahydroborate;
In
tetrahydrofuran;
at 65 ℃;
for 0.25h;
With
methanol;
In
tetrahydrofuran;
at 65 ℃;
stereospecific reaction;
|
70%
|
2.What is the CAS number for L-Methioninol ?
The CAS number of L-Methioninol is 2899-37-8.
More information of L-Methioninol 2899-37-8 are:
|
CAS?Number |
2899-37-8 |
|
Density |
1.068 g/cm3 |
|
Melting Point |
31-33 °C |
|
Boiling Point |
270.2 °C at 760 mmHg |
|
Flash Point |
117.2 °C |
|
Vapor Pressure |
0.000913mmHg at 25°C |
|
Refractive Index |
n20/D 1.5216(lit.) |
|
HS CODE |
29309090 |
|
PSA |
71.55000 |
|
LogP |
0.75940 |
|
Pka |
12.72±0.10(Predicted) |
3.What are another words for L-Methioninol ?
Synonyms?for?L-Methioninol 2899-37-8:(S)-2-Amino-4-methylthio-1-butanol;((S)-1-(Hydroxymethyl)-3-(methylthio)propyl)amine;1-Butanol,2-amino-4-(methylthio)-, (S)-;1-Butanol, 2-amino-4-(methylthio)-, L- (8CI);
4.What is the molecular formula of L-Methioninol?
The chemical formula of ?L-Methioninol is?C5H13NOS which containing 5 Carbon atoms,13 Hydrogen atoms,1 Nitrogen atoms,1 Oxygen atoms and 1 Sulfur atoms,and the molecular weight of??L-Methioninol?is 135.23.
5.What is L-Methioninol (2899-37-8) used for?
L-Methioninol, a methionine derivative, is a white transparent crystalline low melting solid. It is known for its ability to increase bladder excitability by inhibiting stretch-dependent K+ channels.
InChI:InChI=1/C5H13NOS/c1-8-3-2-5(6)4-7/h5,7H,2-4,6H2,1H3/p+1/t5-/m0/s1
Relevant articles related to L-Methioninol:
|
Article |
Source |
|
Green asymmetric synthesis: β-amino alcohol-catalyzed direct asymmetric aldol reactions in aqueous micelles |
Pinaka, Afroditi,Vougioukalakis, Georgios C.,Dimotikali, Dimitra,Yannakopoulou, Elina,Chankvetadze, Bezhan,Papadopoulos, Kyriakos , p. 119 - 125 (2013/08/24) |
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A highly stereoselective synthesis of glycidic amides based on a new class of chiral sulfonium salts: Applications in asymmetric synthesis |
Sarabia, Francisco,Vivar-García, Carlos,García-Castro, Miguel,García-Ruiz, Cristina,Martín-Gálvez, Francisca,Sánchez-Ruiz, Antonio,Chammaa, Samy supporting information, p. 15190 - 15201 (2013/01/15) |
6.Buy L-Methioninol with the best price .
JIANGSU XIANQIAO SPICE TECHNOLOGY CO., LTD is a quality supplier of L-Methioninol. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on L-Methioninol 2899-37-8.
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