1,3-Dimethyl-5-phenylbarbituric acid
- Name 1,3-Dimethyl-5-phenylbarbituric acid
- CAS 7391-66-4
- Purity 99%
Product Details
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1.What is the 1,3-Dimethyl-5-phenylbarbituric acid ?
Used in Pharmaceutical Industry:
1,3-Dimethyl-5-phenylbarbituric acid is used as a sedative and hypnotic medication for the treatment of conditions such as insomnia, anxiety, and epilepsy. Its mechanism of action involves the enhancement of GABA activity, which results in calming and sleep-inducing effects.
However, due to the risks of tolerance, dependence, and withdrawal symptoms associated with its use, the popularity of 1,3-Dimethyl-5-phenylbarbituric acid has diminished in favor of newer, safer sedative-hypnotic drugs. Despite this, it may still be utilized in specific clinical situations where its particular pharmacological profile is deemed necessary.
-
-
96-31-1
N,N'-Dimethylurea
-
-
2613-89-0
phenylmalonic acid
-
-
7391-66-4
1,3-dimethyl-5-phenyl-pyrimidine-2,4,6(1H,3H,5H)-trione
| Conditions | Yield |
|---|---|
|
With
acetic anhydride; trifluoroacetic acid;
In
chloroform; acetic acid;
at 80 ℃;
for 4h;
|
75%
|
|
With
acetic anhydride; acetic acid; trifluoroacetic acid;
In
chloroform;
at 50 ℃;
|
60%
|
|
With
sulfuric acid; acetic anhydride; acetic acid; trifluoroacetic acid;
In
chloroform;
at 70 - 80 ℃;
for 4h;
Inert atmosphere;
|
50%
|
|
With
acetic anhydride; acetic acid; trifluoroacetic acid;
In
chloroform;
at 80 ℃;
for 4h;
Inert atmosphere;
|
50%
|
|
With
acetic anhydride; acetic acid;
|
|
|
With
acetic anhydride; acetic acid; trifluoroacetic acid;
In
chloroform;
at 70 - 80 ℃;
for 4h;
|
-
-
108-86-1,52753-63-6
bromobenzene
-
-
769-42-6
1,3-dimethylbarbituric acid
-
-
7391-66-4
1,3-dimethyl-5-phenyl-pyrimidine-2,4,6(1H,3H,5H)-trione
| Conditions | Yield |
|---|---|
|
With
ytterbium(III) chloride;
In
ethanol;
at 20 ℃;
for 10h;
|
90%
|
2.What is the CAS number for 1,3-Dimethyl-5-phenylbarbituric acid ?
The CAS number of 1,3-Dimethyl-5-phenylbarbituric acid is 7391-66-4.
More information of 1,3-Dimethyl-5-phenylbarbituric acid 7391-66-4 are:
|
CAS?Number |
7391-66-4 |
|
Density |
1.274g/cm3 |
|
Melting Point |
140.0-140.5 °C |
|
Boiling Point |
352.7°Cat760mmHg |
|
Flash Point |
155.2°C |
|
Vapor Pressure |
3.78E-05mmHg at 25°C |
|
Refractive Index |
1.57 |
|
HS CODE |
2933540000 |
|
PSA |
57.69000 |
|
LogP |
0.69640 |
|
Pka |
4.41±0.20(Predicted) |
3.What are another words for 1,3-Dimethyl-5-phenylbarbituric acid ?
Synonyms?for?1,3-Dimethyl-5-phenylbarbituric acid 7391-66-4:Barbituric acid,1,3-dimethyl-5-phenyl- (7CI,8CI); 1,3-Dimethyl-5-phenylbarbituric acid; NSC125776; NSC 128098
4.What is the molecular formula of 1,3-Dimethyl-5-phenylbarbituric acid?
The chemical formula of ?1,3-Dimethyl-5-phenylbarbituric acid is?C12H12 N2 O3 which containing 12 Carbon atoms,12 Hydrogen atoms,2 Nitrogen atoms and 3 Oxygen atoms,and the molecular weight of??1,3-Dimethyl-5-phenylbarbituric acid?is 232.239.
5.What is 1,3-Dimethyl-5-phenylbarbituric acid (7391-66-4) used for?
1,3-Dimethyl-5-phenylbarbituric acid, commonly known as metharbital, is a barbiturate drug characterized by its central nervous system depressant properties. It features a barbituric acid core with two methyl groups at the 1 and 3 positions and a phenyl group at the 5 position, which contributes to its sedative and hypnotic effects by enhancing the activity of the neurotransmitter gamma-aminobutyric acid (GABA) in the brain.
InChI:InChI=1/C12H12N2O3/c1-13-10(15)9(8-6-4-3-5-7-8)11(16)14(2)12(13)17/h3-7,9H,1-2H3
Relevant articles related to 1,3-Dimethyl-5-phenylbarbituric acid:
|
Article |
Source |
|
PHOTOLABILE BARBITURATE COMPOUNDS |
- Page/Page column 26; 27, (2019/08/26) |
|
Method for greenly synthesizing 5-hydroxy-5-alkyl disubstituted barbituric acid derivative by amine catalysis of air oxidation |
- Paragraph 0025; 0027; 0031, (2019/01/07) |
6.Buy 1,3-Dimethyl-5-phenylbarbituric acid with the best price .
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